About
π Trust & Credentials
Why clients trust ACTN3 Bioinformatics:
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9+ Years pharmaceutical industry experience (Roche/Genentech)
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6 Publications in peer-reviewed journals (iScience, Clinical Cancer Research, EMBO MM)
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800+ Patient Samples analyzed across multiple Phase II/III clinical trials
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160K sgRNAs processed in genome-wide CRISPR screens
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ORCID Verified researcher (0000-0003-1714-6105)
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GitHub Public repositories demonstrating technical expertise
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ISO/GxP Aware - understanding of pharmaceutical regulatory requirements
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GDPR Compliant data handling for EU clients
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NDA Standard - confidentiality agreements routine for all projects
π View Publications πΌ LinkedIn Profile π¬ GitHub Repositories
About ACTN3 Bioinformatics
Professional bioinformatics services for biotech, pharma, and academic institutions. We deliver pharma-grade analysis with reproducible workflows and publication-ready results.
π Our Mission
To accelerate scientific discovery by providing expert bioinformatics services that transform complex genomic data into actionable insights. We combine pharma experience, technical excellence, and scientific rigor to support breakthrough research in personalized medicine and drug discovery.
π‘ Why βACTN3β?
ACTN3 is known as the βSpeed Geneβ β encoding a protein that enhances muscle fiber performance and athletic ability. The name symbolizes our core values:
β‘ Speed: Fast turnaround with established pipelines and workflows
πͺ Performance: High-quality, pharma-grade analysis that meets regulatory standards
π― Efficiency: Optimized processes delivering more with less time and resources
Just as ACTN3 powers athletic performance, we power your research with efficient, high-performance bioinformatics.
π¨βπ» Leadership
Szymon Myrta, PhD Candidate
Founder & CEO
Szymon brings 9+ years of bioinformatics experience from Roche/Genentech, where he analyzed clinical trial data for oncology and immunology programs. His expertise spans NGS analysis, R package development, and machine learning for genomics.
Key Credentials: π Cranfield University (Biomedical Engineering) & University of Cambridge (Visiting Student) || π¬ 6 publications in top-tier journals (iScience, Clinical Cancer Research, EMBO MM) || π 800+ patient samples analyzed across multiple Phase II/III trials || 𧬠160,000 sgRNAs processed in genome-wide CRISPR screens || π¦ Expert in R/Bioconductor package development and CRAN standards || π₯ Deep understanding of pharma workflows, GxP, and regulatory requirements
π’ Our Team
ACTN3 Bioinformatics operates as a flexible, expert-driven consultancy. For larger projects, we collaborate with specialized contractors and academic partners to ensure the right expertise for your specific needs.
Our Network Includes: Computational biologists with R/Python expertise || Pipeline engineers (Snakemake/Nextflow) || Machine learning specialists || Biostatisticians for clinical trial analysis || Data visualization experts
This model allows us to: Scale resources based on project requirements || Provide specialized expertise when needed || Maintain competitive pricing || Offer flexible engagement models
πΌ Core Values
π― Reproducibility
Every analysis includes version-controlled code, Docker containers, and comprehensive documentation for full reproducibility.
π Quality
Pharma-grade standards with rigorous QC, statistical best practices, and peer-review-ready outputs.
β‘ Speed
Established pipelines and 9 years of experience mean faster delivery than building in-house.
π€ Partnership
Responsive communication, transparent processes, and collaborative approach to every project.
π Scientific Rigor
Publication-quality analysis backed by deep biological understanding and statistical expertise.
π Confidentiality
NDA compliance, secure data handling, and respect for intellectual property.
π Global Reach
Based in Poland, serving clients worldwide:
Primary Markets: πΊπΈ United States (biotech hubs: San Francisco, Boston, San Diego) || π¬π§ United Kingdom (Cambridge, London) || πͺπΊ European Union (Switzerland, Germany, Netherlands)
Work Arrangements: β Fully remote with 9+ years of remote work experience || β European time zones (flexible for US/Asia collaboration) || β English fluent (C1/C2 scientific communication) || β Polish native
π Experience & Expertise
Industry Experience
Roche/Genentech (via Avenga) β 9+ years
Bioinformatics analysis for oncology and immunology research programs. Clinical trial data analysis (OAK, POPLAR, gp28363 trials), CRISPR screens, scRNA-seq, multi-omics integration.
Ardigen β 2 years
LIMS development and bioinformatics for drug discovery workflows. R package development for internal tools.
Selvita β 1 year
LIMS implementation and ISO compliance coordination for pharmaceutical laboratory systems.
Technical Certifications & Standards
β R/Bioconductor: 9+ years production experience
β CRAN Standards: Package development and submission expertise
β GxP Awareness: Understanding of pharma regulatory requirements
β ISO Experience: Quality management systems for lab operations
β Docker/Singularity: Containerization for reproducibility
β HPC Optimization: Large-scale data processing
Research Output
6 Peer-Reviewed Publications: iScience (2025) β CRISPR screen analysis || Cancer Immunology Research (2024) β NK cell activation || bioRxiv (2023) β scRNA-seq tumor microenvironment || Clinical Cancer Research (2021) β 113-gene classifier || Cancer Research (2020) β AACR abstract || EMBO Molecular Medicine (2013) β CNS remyelination
π¬ Research Interests
Current Focus (2025)
π€ AI in Bioinformatics
LLM-assisted analysis, automated QC, AI-powered variant calling, code generation for genomics workflows
𧬠Multi-Modal Omics
Spatial transcriptomics, single-cell + proteomics integration, epigenomics + transcriptomics correlation
π§ͺ Non-coding RNA
lncRNA, miRNA, circRNA in cancer and development. Integration with mRNA data, regulatory network reconstruction
π¦ Software Development
R package development (Bioconductor standards), Positron IDE workflows, Quarto-based documentation
βοΈ Workflow Engineering
Nextflow DSL2, cloud-native pipelines, CI/CD for bioinformatics, containerization best practices
π― CRISPR & Functional Genomics
Perturb-seq analysis, base/prime editor screens, screen validation workflows, ML for hit prioritization
π₯ Precision Medicine
Real-time clinical decision support, pharmacogenomics, liquid biopsy analysis, patient-specific modeling
π€ How We Work
Our Approach
1. Discovery & Planning
Detailed project scoping, timeline estimation, deliverables definition, and transparent pricing.
2. Regular Communication
Weekly or bi-weekly progress updates, milestone reviews, and collaborative feedback.
3. Rigorous QC
Every step includes quality control checks, statistical validation, and peer review.
4. Comprehensive Documentation
Quarto reports, GitHub repositories, API documentation, and user guides.
5. Post-Project Support
30 days of included support, plus optional maintenance contracts for ongoing projects.
Typical Project Timeline
Small Projects (RNA-seq): 2-4 weeks
Medium Projects (scRNA-seq, R packages): 4-8 weeks
Large Projects (multi-omics, pipelines): 8-16 weeks
Enterprise Partnerships: Custom arrangements
π Compliance & Standards
Data Security: Encrypted transfers, secure cloud storage (AWS/Azure/Google Cloud)
Confidentiality: NDA signing, IP respect, secure data handling
Reproducibility: Version control (Git), containerization (Docker), comprehensive documentation
Quality: Peer-review standards, statistical best practices, rigorous QC
Ethics: Responsible data handling, transparent communication, scientific integrity
π§ Letβs Connect
Interested in working together? Weβd love to hear about your project.
π§ Contact Us πΌ LinkedIn π View Portfolio
Email: kontakt@actn3.pl
Response Time: Within 24 hours
Availability: International projects welcome